AGC Biologics GmbH

PD Scientist Downstream Process Development- Proteins and pDNA

Heidelberg
Feste Anstellung
Vollzeit

Einleitung

AGC Biologics, a wholly-owned subsidiary of Asahi Glass Company (AGC), is one of the industry leading CDMOs in reliability, technical excellence, and quality — Right and On Time. AGC is a $12B Japanese-owned and publicly traded company based in Tokyo with over 50,000 employees in 30 countries.

With facilities in the USA, Japan, Denmark and Germany, AGC Biologics provides fully integrated biopharmaceutical development and manufacturing solutions to clients globally. The Company has proven expertise in delivering custom solutions for the scale-up and cGMP manufacture of protein-based therapeutics for pre-clinical, clinical, and commercial production.

AGC Biologics is experiencing growth in customer base and revenue, expanding personnel, development and manufacturing capacity as well as distinguishing itself in the market with unique technology offerings for clients.

Job Summary:

AGC Biologics GmbH is currently looking for an expert to join the Downstream Process Development, DSP subdivision of the Process Development (PD) team in Heidelberg. The ideal candidate is a part of the DSP team and responsible for the establishment of purification processes for protein and plasmid DNA microbially produced. This includes also all needed steps related on DSP development and analytical steps and reporting associated with DSP.

Ihre Aufgaben

Jobholder has emphasis to develop/establish processes for the purification of proteins and pDNA from microbial lysates or refolding
Develop/establish processes incl. precipitation and stability studies of the targets to support purification
Develop/establish intermediate steps required for purification of desired targets
Planning and evaluation of the experiments by adequate analytical methods
Adaptation of existing analytical methods on protein/project requirements and support of Analytical Development subdivision of PD
Preparing and presenting data associated with DSP for internal and external purposes (preparation of reports and presentations summarizing DSP work)
Assisting lab work and report this to the PD and DSP representative
Supporting search, implementation of new technologies and tools related on DSP into PD to
expand PD DSP capabilities and improve processes
Supporting Manufacturing and QC on drafting and revising manufacturing batch records and SOPs
Assisting communication with the client
Preparing and presenting data associated with DSP for internal and external purposes
Assisting effective working relationships with QC, QA, Manufacturing, Project Management and
Business Development to support new processes, products and projects
Other duties as assigned

Ihr Profil

Ph.D. in Biotechnology, Biochemistry or related engineering or university discipline with +5 years of expertise and main emphasis in Process development; especially strong knowledge in Downstream Development is preferred (well-grounded knowledge in this field should be proven by the candidate)
Alternatively: Master’s degree in Engineering, Science or with minimum of +8 years of direct relevant experience (same spectrum of knowledge is mandatory) may also be desirable, road insights and experiences in PD DSP based technologies, technical skills on industry level is desirable
Ideal candidate has prolonged industrial background
Ideally, familiar with data mining, DoE quality tools, analysis and process control
Must be self-motivating, organized and proactive in order to coordinate the multi-departmental tasks
Broad insights and experiences in PD DSP based technologies, technical skills on industry level is desirable
Ideally, familiar with data mining, DoE quality tools, analysis and process control
and deliverables (interaction with Manufacturing, QA, QC, et cetera)
Requirement of minimal supervision
Attitude for successful handling multiple projects in parallel
Experience with transition from development to production
Strong presentation skills
Strong technical attitude including experience of applying scientific reasoning to solve complex problems
Flexibility to tackle challenges in new projects/areas
Fluent in verbal and written German and English
German work permit is mandatory
Ability to communicate technical know-how
Attention to detail
Ability to integrate in an existing team and to perform as a team player

Wir bieten

Join an international and agile organization

AGC Biologics offers a dynamic working place with good opportunities of working with a varied array of tasks and challenges. You will get insight into and experience with the way the various departments throughout a contract manufacturing organization interact in order to achieve success. Exciting and challenging assignments will constantly come your way, and you will to a large extent be able to plan your daily work yourself. AGC Biologics offers an informal working environment, where humor is part of the daily work life. We respect each other and our individual differences. AGC Biologic’s employees have a flexible attitude and we help each other to reach deadlines together as one team.

Weitere Informationen

Send your application using the APPLY bottom below (please note, only applications received through the APPLY bottom will be processed) as soon as possible and not later than March 31^th 2021. We process the applications as we receive them, and qualified applicants can expect to be interviewed before the deadline. For further information regarding the position, please do not hesitate to contact Dr. Mario Kraft, Head Process Development, email: mkraft@agcbio.com. We look forward to hearing from you.

AGC Biologics GmbH

Czernyring 22
69115 Heidelberg

http://www.agcbio.com/